Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 121
Filter
1.
Journal of Prevention and Treatment for Stomatological Diseases ; (12): 161-168, 2024.
Article in Chinese | WPRIM | ID: wpr-1006506

ABSTRACT

@#After tooth extraction, significant absorption occurs in the soft and hard tissues of the alveolar ridge. The goal of alveolar ridge preservation is to maintain the volume and shape of the alveolar ridge's soft and hard tissues as much as possible so as to provide suitable conditions for implant placement. Currently, there are challenges in classifying the socket for alveolar ridge preservation, such as the difficulty in directly guiding the selection of graft materials and clinical procedures and the insufficient space for particle xenograft maintenance, resulting in poor bone regeneration. Plasmatrix is an autologous blood derivative that effectively enhances tissue regeneration. This article introduced the characteristics of soft and hard tissue defects after tooth extraction and the primary applications of plasmatrix for alveolar ridge preservation (liquid plasmatrix, solid plasmatrix membrane/plug, and plasmatrix bone blocks) as well as the proposed methods for the reclassification of sockets for alveolar ridge preservation based on soft and hard tissue defects at the extraction site to facilitate the creation of clinical recommendations. The proposed classifications are as follows: Class I, extraction socket without bone defect, with or without soft tissue defect; Class Ⅱ, extraction socket with bone defect, both sides with bone wall defect less than 50%, with or without soft tissue defect; Class Ⅲ, extraction socket with bone tissue defect, at least one side with bone wall defect greater than 50%, with or without soft tissue defect. For the Class I socket, a solid plasmatrix membrane or plug is inserted, followed by injection of liquid plasmatrix, using a double-layer solid plasmatrix membrane for socket closure; for the ClassⅡ socket, plasmatrix bone blocks are inserted, followed by injection of liquid plasmatrix and secondary solidification, using absorbable collagen membrane and double-layer solid plasmatrix membrane for socket closure; for the ClassⅢ socket, tenting screws are used to maintain height, followed by implantation of plasmatrix bone blocks, injection of liquid plasmatrix and secondary solidification, using absorbable collagen membrane and double-layer solid plasmatrix membrane for socket closure. The aim of this article is to provide comprehensive knowledge of plasmatrix for oral clinicians to serve as a reference to simplify the clinical decision-making process and procedures for alveolar ridge preservation.

2.
Journal of Prevention and Treatment for Stomatological Diseases ; (12): 57-63, 2024.
Article in Chinese | WPRIM | ID: wpr-1003446

ABSTRACT

Objective@#To investigate the effect of the socket-shield technique (SST) concurrent with immediate implant placement and provisionalization (IIPP) in the aesthetic restoration of anterior teeth.@*Methods@#A case of maxillary anterior tooth stumps with a thin labial bone wall was treated with SST for preservation of labial soft and hard tissue fullness, combined with an immediate implant placement and immediate provisional crown for restoring the shape of the tooth and gingival molding@*Results@#Immediate implant placement and provisionalization restored the morphology and function of the affected tooth in the shortest possible time. The patient's labial soft and hard tissue contours in the affected tooth area were well preserved in the 18-month follow-up after the application of the SST, which presented a better aesthetic result. The literature review indicates that the indications for SST are unrestorable maxillary anterior teeth, whose dental, periodontal and periapical tissues are healthy and intact. In the esthetic zone, root shielding is effective in maintaining the soft and hard tissue contour on the labial side of the implant. However, there is no consensus on the technical details of SST, such as the ideal coronal height and thickness of the shield, and the management of the gap between the shield and the implant. Thus, more clinical studies and histologic evidence are needed to provide a reference for clinical decision-making. In addition, digital technology can improve the accuracy of implant placement and shield preparation.@*Conclusion@#The correct application of SST combined with IIPP in the esthetic zone can ensure esthetic results. However, more high-quality evidence-based medical evidence is needed for its long-term efficacy, and indications should be strictly controlled during clinical application.

3.
Rev. cir. traumatol. buco-maxilo-fac ; 23(2): 8-16, abr./jun 2023. ilus, tab
Article in English | LILACS, BBO | ID: biblio-1537341

ABSTRACT

Introduction: The intentionally exposed polypropylene (PP) membrane has been proposed for guided bone regeneration (GBR) of the alveo lar bone after extraction; however, there are biological limitations to this proposal. This study aimed to describe the effects of the PP membrane on neo-osteogenesis after tooth extraction, comparing to intentionally ex posed and primary soft tissue coverage techniques. Methodology: This clinical trial followed the TIDieR checklist and guide. Clinical and histo logical parameters of alveolar repair were compared between groups: 1 (control group), without regenerative procedure; 2, GBR; and 3, inten tionally exposed membrane. Results: Group 3 showed slight effect on the quality of new bone, compared to the control group. Although the GBR was underestimated by the early exposure of the membrane, alveo lar repair and newly formed bone were superior to the other groups. Poly propylene membrane intentionally exposed compromised the volume density of the immature and mineralized bone matrix, the osteoblast and osteocyte count, and stimulated the granulation tissue formation and local inflammatory infiltrate. Conclusions: Despite the exposure of the PP membrane in GBR, this technique improved the quality of new bone and alveolar repair compared to the surgical technique of intentional exposure and alveolus only sutured.


RESUMEN Introducción: La membrana de polipropileno (PP) intencionalmente expuesta ha sido propuesta para la regeneración ósea guiada (GBR) del hueso alveolar después de la extracción; sin embargo, existen limitaciones biológicas a esta propuesta. Este estudio tuvo como objetivo describir los efectos de la membrana de PP en la neo-osteogénesis después de la extracción del diente, en comparación con las técnicas de cobertura de tejido blando primarias y expuestas intencionalmente. Metodología: Este ensayo clínico siguió la lista de verificación y la guía TIDieR. Se compararon los parámetros clínicos e histológicos de la reparación alveolar entre los grupos: 1 (grupo control), sin procedimiento regenerativo; 2, GBR; y 3, membrana expuesta intencionalmente. Resultados: el grupo 3 mostró un ligero efecto sobre la calidad del hueso nuevo, en comparación con el grupo de control. Aunque la GBR fue subestimada por la exposición temprana de la membrana, la reparación alveolar y el hueso neoformado fueron superiores a los otros grupos. La membrana de polipropileno expuesta intencionalmente comprometió la densidad de volumen de la matriz ósea inmadura y mineralizada, el recuento de osteoblastos y osteocitos, y estimuló la formación de tejido de granulación y el infiltrado inflamatorio local. Conclusiones: A pesar de la exposición de la membrana de PP en GBR, esta técnica mejoró la calidad del hueso nuevo y la reparación alveolar en comparación con la técnica quirúrgica de exposición intencional y alvéolo solo suturado.


Introdução: A membrana de polipropileno (PP) intencionalmente exposta tem sido proposta para regeneração óssea guiada (ROG) do osso alveolar após exodontia; no entanto, existem limitações biológicas a esta proposta. Este estudo teve como objetivo descrever os efeitos da membrana de PP na neo-osteogênese após a extração dentária, comparando com as técnicas de exposição intencional e cobertura primária de tecidos moles. Metodologia: Este ensaio clínico seguiu a lista de verificação e o guia TIDieR. Parâmetros clínicos e histológicos do reparo alveolar foram comparados entre os grupos: 1 (grupo controle), sem procedimento regenerativo; 2, GBR; e 3, membrana intencionalmente exposta. Resultados: O Grupo 3 apresentou leve efeito na qualidade do novo osso, em comparação com o grupo controle. Embora o GBR tenha sido subestimado pela exposição precoce da membrana, o reparo alveolar e o osso neoformado foram superiores aos outros grupos. A exposição intencional da membrana de polipropileno comprometeu a densidade volumétrica da matriz óssea imatura e mineralizada, a contagem de osteoblastos e osteócitos e estimulou a formação de tecido de granulação e infiltrado inflamatório local. Conclusões: Apesar da exposição da membrana PP na ROG, esta técnica melhorou a qualidade do novo osso e da reparação alveolar em comparação com a técnica cirúrgica de exposição intencional e alvéolo apenas suturado.


Subject(s)
Humans , Polypropylenes , Bone Regeneration , Tooth Socket , Guided Tissue Regeneration , Alveolar Ridge Augmentation
4.
Rev. nav. odontol ; 50(2)20232010.
Article in Portuguese, English | LILACS-Express | LILACS | ID: biblio-1518567

ABSTRACT

A utilização da tecnologia CAD/CAM (computer aided design/computer aided manufacturing) e 3D (tridimensional) para reconstruções alveolares na implantodontia permite o planejamento pré-operatório detalhado, o design do resultado desejado do enxerto e a avaliação virtual do resultado em relação à reconstrução protética. Este trabalho objetiva detalhar a técnica cirúrgica de enxerto ósseo sintético confeccionado por meio dessa tecnologia, seguido da instalação de implantes osseointegráveis e reabilitação protética em um defeito ósseo na mandíbula. Paciente masculino, 22 anos, compareceu à clínica por avulsão dos elementos 32, 31, 41 e 42 com significativa perda óssea vertical de rebordo alveolar. Devido à extensa perda óssea, realizou-se enxerto em bloco prototipado impresso. O escaneamento intraoral e os arquivos de imagem gerados foram enviados ao centro de planejamento virtual. Primeiramente, foi realizada a cirurgia para instalação do enxerto em bloco. Após o período de cicatrização, foi realizada cirurgia para instalação de dois implantes osseointegráveis. Esperado o período de três meses a partir da instalação dos implantes, foi realizada a confecção de próteses provisórias fixas sobre implantes a fim de realizar o condicionamento dos tecidos moles peri-implantares e o carregamento progressivo dos implantes. O aumento do rebordo alveolar através do uso de enxerto em bloco impresso personalizado apresentou-se como uma técnica com inúmeras vantagens, por não necessitar de sítio doador, reduzir tempo cirúrgico e apresentar perfeita adaptação do bloco ao defeito ósseo, resultando em menor morbidade pós-operatória. Essa técnica é uma indicação para casos de defeitos ósseos severos, visando a otimizar o resultado e a propiciar menor desconforto ao paciente.


The use of the technology CAD/CAM (computer aided design/computer aided manufacturing) and 3D (three dimensional) to alveolar reconstructions in implant dentistry allows detailed preoperative planning, the design of the desired grafting result, and the virtual evaluation of the result in relation to the prosthetic reconstruction. This paper aims to details the synthetic bone graft made through this technology, followed by the installation of osseointegrated implants and prosthetic rehabilitation in a bone imperfection in the jaw. A 22-year-old man attended the clinic due to a tooth avulsion of the four lower incisors with significant vertical bone loss of alveolar ridge. Because of the extensive bone loss, it was made a prototyped printed block graft. The intraoral scan and the generated image files were sent to the virtual planning center. First, it was necessary a surgery to install the block graft. After the healing process, it was made a surgery to put two osseointegrated implants. Three months later, temporary fixed prostheses on implants were made to conditioning the peri-implant soft tissues and the progressive loading of the implants. The increase of the alveolar ridge using personalized printed block graft was presented as a technique with numerous advantages, since it does not require a donor site, reduces the surgical time and presents perfect adaptation of the block to the bone imperfection, resulting in a less postoperative morbidity. This technique is indicated to cases of severe bone imperfections, aims to optimize results, and provide less discomfort to the patient.

5.
RFO UPF ; 27(1)08 ago. 2023. tab, ilus
Article in Portuguese | LILACS, BBO | ID: biblio-1511050

ABSTRACT

Objetivo: revisar a literatura sobre os diferentes tipos de derivados de plaquetas autólogas e o desempenho clínico do uso do sticky bone para aumento ósseo horizontal de rebordo. Materiais e métodos: Para realização dessa revisão foram realizadas buscas nas bases de dados PubMed, Google Scholar e Web of Science, utilizando os seguintes descritores: "platelet-rich fibrin" AND "sticky bone" OR "alveolar bone grafting" AND "sticky bone" OR "guided bone regeneration" AND "sticky bone" AND "alveolar ridge augmentation" OR "Alveolar ridge augmentation" AND "sticky bone". Foram incluídos artigos publicados em inglês, que abordavam conceitos relacionados aos agregados plaquetários e a regeneração óssea guiada para aumento ósseo horizontal de rebordo utilizando fibrina rica em plaquetas associada à enxertos ósseos (sticky bone). Resultados: Após avaliação dos estudos encontrados foram selecionados 11 artigos sobre o uso do sticky bone para aumento horizontal de rebordo. Para compor este trabalho foram selecionados também 14 estudos de revisão e artigos associados ao tema. Por ser de fácil aplicação e obtenção, muitos autores têm estudado as aplicações cirúrgicas do sticky bone e os resultados demonstram que o aumento horizontal do rebordo utilizando essa técnica pode ser realizado de forma previsível. Conclusão: apesar de haver estudos promissores sobre o uso do sticky bone, falta evidência na literatura sobre seu sucesso clínico. Assim, para compreender o potencial regenerativo desta técnica são necessários um maior número de estudos randomizados, com diferentes materiais de enxerto e protocolos padronizados de obtenção do sticky bone.(AU)


Objective: to review the literature on the different types of autologous platelet derivatives and the clinical performance of using sticky bone for horizontal bone ridge augmentation. Materials and methods: In order to conduct this review, it was conducted searches in the PubMed, Google Scholar, and Web of Science databases using the following descriptors: "platelet-rich fibrin" AND "sticky bone" OR "alveolar bone grafting" AND "sticky bone" OR "guided bone regeneration" AND "sticky bone" AND "alveolar ridge augmentation" OR "Alveolar ridge augmentation" AND "sticky bone". It included articles published in English that addressed concepts related to platelet aggregates and guided bone regeneration for horizontal bone augmentation using platelet-rich fibrin associated with bone grafts (sticky bone). Results: After evaluating the studies found, were selected 11 articles on the use of sticky bone for horizontal ridge augmentation. To compose this work, 14 review studies and articles associated with the topic were also selected. Due to its ease of application and availability, many authors have explored the surgical applications of sticky bone, and the results indicate that horizontal ridge augmentation using this technique can be predictably performed. Conclusion: while there are promising studies on the use of sticky bone, the literature lacks evidence regarding its clinical success. Therefore, to fully understand the regenerative potential of this technique, further randomized studies are needed, involving different graft materials and standardized protocols for obtaining sticky bone.(AU)


Subject(s)
Humans , Guided Tissue Regeneration/methods , Alveolar Ridge Augmentation/methods , Alveolar Bone Grafting/methods , Platelet-Rich Fibrin , Bone Regeneration/physiology
6.
STOMATOLOGY ; (12): 159-165, 2023.
Article in Chinese | WPRIM | ID: wpr-979297

ABSTRACT

@#Alveolar ridge preservation (ARP) has developed rapidly as a method for preserving the alveolar socket's bone volume after tooth extraction. ARP can create conditions for implant restoration, and reduce operation difficulties by decreasing alveolar ridge absorption. There are certain difficulties of ARP applicationin patients with tooth extracted due to periodontitis. This paper mainly introduces the characteristics of ARP, compares the similarities and differences among ARP, guided tissue regeneration, guided bone regeneration and immediate implant, and then summarizes their advantages and disadvantages. The paper focuses on the specificity of ARP and the progress of ARP application in patients with tooth extracted due to periodontitis, in order to offer direction for clinical application and future research on ARP.

7.
Journal of Prevention and Treatment for Stomatological Diseases ; (12): 278-283, 2023.
Article in Chinese | WPRIM | ID: wpr-961207

ABSTRACT

Objective @#To explore the etiology, clinical manifestations, diagnosis and treatment of multiple idiopathic root resorption to provide a reference for clinical diagnosis and treatment. @*Methods@# The clinical data of a case of multiple idiopathic root resorption were analyzed retrospectively, and the related literature was reviewed.@*Results@#The patient had no history of orthodontic correction, occlusal trauma, trauma history or other causes of root resorption. Clinical examination revealed full-mouth gingival congestion, redness, a loose texture, and variable degrees of destruction of the alveolar bone. Imaging examination showed that teeth 13, 16, 26, 36, 46 had idiopathic root resorption. The diagnoses were multiple idiopathic root resorption and periodontitis. The pathology tests showed that a large number of osteoclasts were present in the soft tissue surrounding the teeth. Whole-exome sequencing showed that there was a strong correlation between gene mutations (WNT7a and HSPG2) and the present phenotype. Root resorption of teeth without periodontitis was stopped after periodontal treatment during the 19-month follow-up. Tooth 13 was removed, and extraction socket preservation was performed. The etiology of idiopathic root resorption may be related to gene mutations, but it is not clear. At present, there is no effective treatment. @* Conclusion @#Multiple idiopathic root resorption has an unknown etiology, but it may be related to WNT7A and HSPG2 gene mutations. The rate of root resorption can be slowed by controlling periodontal inflammation.

8.
Journal of Prevention and Treatment for Stomatological Diseases ; (12): 153-161, 2023.
Article in Chinese | WPRIM | ID: wpr-960873

ABSTRACT

@#Ideal sutures can provide great fixation, wound closure and a stable environment for healing of the surgical site. Tension-free apposition sutures are important for tissue regeneration and could tackle insufficient amounts of soft and hard tissue, especially in missing tooth sites that require implantation. The internal horizontal mattress suture, similar to the conventional horizontal mattress suture, forms a rectangle that can be bisected by the incision with both intrusion and extrusion of the needle on each side. On the basis of the rectangle, the internal horizontal mattress suture emphasizes that the suture should be located below the incision, so the eversion of the wound margin is the highlight of this procedure. The internal horizontal mattress suture could stabilize the graft on the targeting tissue, realize the fixation of the collagen membrane, apically repositioned flap and soft tissue graft, reduce the tension on the incision, and further release the tension of the incision margin. Beyond the primary need for fixation and wound closure, internal horizontal mattress sutures can also achieve stress interruption that reduces the interference of the surrounding muscle and can better master wound tension with the assistance of interrupted sutures. Given the above advantages, horizontal internal mattress sutures have great potential in the application of implant-related regenerative surgery. In this review, according to our experience in clinical practice and the literature, we summarize the advantages of internal horizontal mattress sutures in tissue augmentation. In addition, the sites and sequence to insert the needle and the spatial relationship between the suture and incision are clarified with the rationale of the naming pattern, which is conducive to experience exchange and clinical practice.

9.
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1405306

ABSTRACT

RESUMEN: Actualmente existen varias alternativas para prevenir, disminuir y corregir deformidades en el reborde alveolar, originadas por la reabsorción ósea al momento de la extracción de uno o varios dientes. La preservación alveolar es cualquier procedimiento que se realiza al momento de una extracción y permite conservar las dimensiones y el contorno del alveolo. Hay diversas técnicas para preservación las cuales están diseñadas para prevenir tanto como sea posible los cambios ocurridos al retirar un órgano dentario. El tratamiento de elección para reemplazar la funcionalidad, estabilidad biológica y estética de un diente, es a través de la colocación de implantes dentales, cuya colocación posterior a la preservación alveolar reduce los cambios dimensionales del reborde alveolar. La recientemente propuesta técnica de preservación alveolar BARP, "Biologically-oriented Alveolar Ridge Preservation" por sus siglas en Inglés, logró preservar las dimensiones de la cresta alveolar, al tiempo que restringe cualquier interferencia sobre el biomaterial.


ABSTRACT: Nowadays there are several choices, to prevent, reduce and correct alveolar ridge deformities caused by resorption at the time of extracting one or several teeth. Alveolar ridge preservation is defined as any procedure performed, following any dental extraction that allows the dimensions of the alveolus to be preserved. Those techniques of alveolar ridge preservation are designed to prevent as many reabsorption changes that occur after dental extraction. The best choice to replace the functionality, biological stability, and esthetic, of natural teeth is to place a dental implant. The placement of the alveolar ridge preservation treatment reduces the dimensional changes over the alveolar ridge. The recently proposed technique to alveolar ridge preservation called BARP or "Biologically-oriented Alveolar Ridge Preservation" managed to preserve the alveolar ridge dimensions while restricting any interference with the biomaterial at the same time.

10.
Braz. dent. j ; 33(3): 82-91, July-Sept. 2022. graf
Article in English | LILACS-Express | LILACS, BBO | ID: biblio-1384027

ABSTRACT

Abstract The aim of this study was to evaluate a Demineralized Human Dentine Matrix (DHDM) as viable biomaterial for alveolar ridge preservation in a rat model. Wistar rats were submitted to the extraction of maxillary first molars bilaterally. Sockets were filled with biomaterials and divided into 4 experimental groups (n=5): blood clot, autogenous bone, bovine-derived xenograft (BDX) and DHDM. Animals were sacrificed at 7, 14 e 28 days. Microtomography (uCT) volumetric evaluation and qualitative histological analyses were performed. Results obtained through the uCT showed similar values between the DHDM and the other experimental groups. The histological evaluation demonstrated DHDM with an unspecific inflammatory process and bone neoformation with slow reabsorption of the material. This result indicates that DHDM implanted in rat sockets is biocompatible and reduces the alveolar ridge volume loss after tooth extraction.


Resumo O objetivo deste estudo foi avaliar a Matriz Dentinária Humana Desmineralizada (MDHD) como biomaterial viável para preservação do rebordo alveolar, no modelo em rato. Ratos Wistar foram submetidos à exodontias dos primeiros molares superiores bilateralmente. Os alvéolos foram preenchidos com biomateriais e divididos em 4 grupos experimentais (n=5): coágulo sanguíneo, osso autógeno, osso xenógeno de origem bovina e MDHD. Os animais foram sacrificados aos 7, 14 e 28 dias. Foram realizadas avaliações volumétricas por microtomografia (uCT) e análises histológicas qualitativas. Os resultados obtidos por meio do uCT mostraram valores semelhantes entre o MDHD e os demais grupos experimentais. A avaliação histológica demonstrou MDHD com processo inflamatório inespecífico e neoformação óssea com lenta reabsorção do material. Esse resultado indica que a MDHD implantada em alvéolo de rato é biocompatível e reduz a perda de volume do rebordo alveolar após extração dentária.

11.
Rev. cir. traumatol. buco-maxilo-fac ; 22(3): 32-39, jul.-set. 2022. ilus
Article in Portuguese | LILACS, BBO | ID: biblio-1399763

ABSTRACT

Introdução. Decorrente do trauma local, durante a exodontia, ou pela falta de estímulos mastigatórios, a ausência dentária promove respostas biológicas que desencadeiam um processo de reabsorção óssea. A preservação óssea alveolar propõe minimizar a reabsorção óssea alveolar, promovendo maior biodisponibilidade óssea para a reabilitação por implantes dentários. Os implantes dentários são uma modalidade terapêutica eficaz para a reabilitação de ausências dentárias. Objetivo. relatar um caso de reabilitação por implante em alvéolo cicatrizado, após preservação alveolar. Relato de caso. Paciente A.L.L., sexo masculino, 23 anos, compareceu à clínica odontológica da UNIBRA. Ao exame físico observou-se ampla destruição coronária do elemento 25 e, ao exame radiográfico notou-se tratamento endodôntico. O tratamento proposto foi a exodontia minimamente traumática, preservação alveolar com matriz de colágeno e instalação de implante dentário em alvéolo cicatrizado. Discussão. Em desdentados, a falta de estímulos mastigatórios, promove um desequilíbrio no turnover ósseo, desencadeando um processo de reabsorção. A preservação alveolar por matriz de colágeno visa minimizar a reabsorção e fornecer maior biodisponibilidade óssea para a reabilitação por implantes. Conclusão. A preservação alveolar com a matriz de colágeno cumpriu com seu objetivo e, a reabilitação por implante dentário em alvéolo cicatrizado é uma modalidade eficaz na reabilitação de pacientes desdentados... (AU)


Introduction. Due to local trauma, during tooth extraction, or the lack of masticatory stimuli, the absence of teeth promotes biological responses that trigger a process of bone resorption. Alveolar bone promotion minimizes alveolar bone resorption, promoting high bone bioavailability for rehabilitation with dental implants. Dental implants are a treatment modality to edentulous. Objective. Report a case of implant rehabilitation in a healed socket after alveolar preservation. Case report. Patient A.L.L., male, 23 years old, attended the UNIBRA dental clinic. On physical examination, a wide coronary destruction of element 25 was observed and, on radiographic examination, endodontic treatment was noted. The proposed treatment was a minimally traumatic tooth extraction, alveolar preservation with collagen matrix and implant placement in healed sockets. Discussion. In edentulous patients, the lack of masticatory stimuli promotes an imbalance in bone turnover, triggering a resorption process. Alveolar preservation by collagen matrix aims to minimize resorption and provide greater bone bioavailability for implant rehabilitation. Conclusion. Alveolar preservation with collagen matrix fulfilled its objective, and rehabilitation by dental implant in a healed socket is an effective modality in the rehabilitation of edentulous patients... (AU)


Introducción. Por traumatismo local, durante la extracción dentaria, o por falta de estímulos masticatorios, la ausencia de dientes promueve respuestas biológicas que desencadenan un proceso de reabsorción ósea. La preservación ósea alveolar propone minimizar la reabsorción ósea alveolar, promoviendo una mayor biodisponibilidad ósea para la rehabilitación mediante implantes dentales. Los implantes dentales son una modalidad terapéutica eficaz para la rehabilitación de dientes perdidos. Objetivo. reportar un caso de rehabilitación con implantes en un alvéolo cicatrizado después de preservación alveolar. Reporte de un caso. Paciente A.L.L., masculino, 23 años, acudió a la clínica odontológica de la UNIBRA. El examen físico reveló destrucción coronaria extensa del elemento 25 y el examen radiográfico reveló tratamiento endodóntico. El tratamiento propuesto fue extracción dental mínimamente traumática, preservación alveolar con matriz de colágeno y colocación de implante dental en alvéolo cicatrizado. Discusión. En pacientes edéntulos, la falta de estímulos masticatorios promueve un desequilibrio en el recambio óseo, desencadenando un proceso de reabsorción. La preservación alveolar mediante matriz de colágeno tiene como objetivo minimizar la reabsorción y proporcionar una mayor biodisponibilidad ósea para la rehabilitación con implantes. Conclusión. La preservación alveolar con matriz de colágeno cumplió su objetivo, y la rehabilitación mediante implante dental en un alvéolo cicatrizado es una modalidad eficaz en la rehabilitación de pacientes edéntulos... (AU)


Subject(s)
Humans , Male , Young Adult , Surgery, Oral , Bone Resorption , Dental Implants , Alveolar Ridge Augmentation , Mouth Rehabilitation , Tooth Extraction , Tooth Injuries , Molar/surgery
12.
J. oral res. (Impresa) ; 11(2): 1-28, may. 23, 2022. tab
Article in English | LILACS | ID: biblio-1400827

ABSTRACT

Introduction: There are multiple techniques for vertical bone augmentation. Guided bone regeneration is one of them; however, the literature is diverse and includes different study designs, which makes it difficult to synthesize results. Objective: To analyze the general technical characteristics, clinical results, and complications of vertical bone augmentation performed with guided bone regeneration in humans. Material and Methods: This scoping review was based on the PRISMA-ScR guidelines. A search was performed in the Pubmed, Scielo, and Worldcat databases. Papers published from 1990 to April 2020 were included in the study. Research articles not conducted in humans or published in languages other than English and Spanish were excluded. Title and abstract were screened by two reviewers, then full studies were extracted, and data tabulated. Results: 89 studies were included. The highest percentage reported having obtained a vertical bone increase of less than 5 mm and having used non-resorbable membranes. The most frequent type of graft is autogenous and combinations of grafts, the most common being autogenous with xenograft. All studies that reported bone stability of implants in regenerated bone were favorable, as was implant survival, reporting values between 83.8% and 100%. Membrane exposure is the most frequently reported complication, followed by infection or abscesses, and tissue dehiscence. Conclusion: Vertical bone regeneration is a reliable technique, with high predictability and low incidence of complications compared to other vertical bone augmentation techniques.


Introducción: Existen múltiples técnicas para el aumento óseo vertical siendo una opción la regeneración ósea guiada, sin embargo, la literatura es diversa y con distintos diseños que dificultan la síntesis de resultados. Objetivo: Analizar las características generales técnicas, resultados clínicos y complicaciones del aumento óseo vertical realizado con regeneración ósea guiada en humanos. Material y Métodos: Esta revisión de alcance se basó en la guía PRISMA-ScR. Se realizó una búsqueda en las bases de datos Pubmed, Scielo y Worldcat. Fueron incluidos aquellos publicados desde el año 1990 hasta abril de 2020. Se excluyeron los estudios no realizados en humanos o publicados en idiomas distintos al inglés y español. Dos revisores examinaron título y resumen, luego los estudios completos se extrajeron y se ordenaron los datos en tablas. Resultados: 89 estudios fueron incluidos. El mayor porcentaje reportó haber obtenido un aumento óseo vertical menor a 5 mm y haber utilizado membranas no reabsorbibles. El tipo de injerto que más frecuente es el autógeno y las combinaciones de injertos, siendo el más común autógeno con xenoinjerto. Todos los estudios que reportaron estabilidad ósea de implantes en hueso regenerado fueron favorables, al igual que la supervivencia de implantes, reportando valores entre 83,8% y 100%. La exposición de membrana es la complicación que más se repite en los estudios, seguido por infección o abscesos y dehiscencia de tejidos. Conclusión: La regeneración ósea vertical es una técnica confiable, con alta predictibilidad y baja incidencia de complicaciones en comparación a otras técnicas de aumento óseo vertical.


Subject(s)
Humans , Bone Regeneration , Dental Implants , Guided Tissue Regeneration, Periodontal , Alveolar Ridge Augmentation/methods , Alveolar Bone Loss , Transplants , Alveolar Process
13.
Archives of Orofacial Sciences ; : 119-127, 2022.
Article in English | WPRIM | ID: wpr-964091

ABSTRACT

ABSTRACT@#Alveolar ridge preservation is a surgical procedure aimed to preserve the alveolar bone after tooth extraction to eliminate or reduce the need for bone augmentation during implant placement. It includes the use of membrane that is either being used alone or in combination with a bone replacement graft. This case report describes the technique of alveolar ridge preservation after tooth extraction using a xenogenic bone graft combined with a resorbable collagen membrane, and the fabrication of an anterior fibre-reinforced composite (FRC) bridge in an 18-year-old male patient. This treatment allows him to have a good preservation of the volume and architecture of the alveolar ridge as well as soft tissues and temporarily replace a missing anterior tooth until a definitive restoration can be achieved.


Subject(s)
Young Adult , Alveolar Ridge Augmentation , Tooth Extraction , Composite Resins
14.
Article in English | LILACS-Express | LILACS | ID: biblio-1385783

ABSTRACT

ABSTRACT: The present study investigated the healing response of 12 fresh post-extraction alveolous grafted with particulate autologous teeth to achieve preservation of the post-extraction alveolar ridge. The objective is to elucidate the osteoconductive and osteoinductive properties of the autologous dental graft used as a bone substitute in the alveolar ridge preservation technique. Five patients were included, with at least one hopeless tooth and in need of extraction and preservatio n of the ridge, to receive in the same place a dental implant in prosthetic replacement. In the first surgical stage, dental extractions and preservation of the alveolar ridge were performed, using the teeth extracted and processed with an automatic system as bone substitutes. In the second surgical stage, an incisional bone biopsy was performed in each grafted site, the bone beds were recapitulated in a drilling protocol that allowed the placement of the dental implant, and the harvested bone specimens were prepared for analysis. The histological results of the bone biopsies in all cases showed remnant particles of the dental graft, made up of dentin, partially resorbed, with irregular superficial edges and in close contact with newly forme d bone in transition to mature lamellar bone, in which well differentiated osteocytes were observed. The immunohistochemical results showed a moderate positive expression of osteopontin at the edges of the integrated teeth particles, inside the peritubular dentin space and at the osteodental contact interfaces. In conclusion, the evidence from the study shows that the autologous dental graft is a biocompatible bone substitute, that provides an osteoconductive scaffold that promotes bone cell adhesion and migration for local osteogenesis and that it is associated with moderate in situ expression of osteopontin, which showed a high affinity with mineralized dental tissue, suggesting osteoinductive properties in situ.


RESUMEN: El presente estudio investigó el resultado cicatrizal de 12 alvéolos frescos postextracción injertados con dientes autólogos particulados para lograr la preservación del reborde alveolar postextracción. El objetivo es dilucidar las propiedades osteoconductivas y osteoinductivas del injerto dental autólogo utilizado como sustituto óseo en la técnica de preservación de reborde. Se incluyeron 5 pacientes, con al menos un diente sin esperanza y con necesidad de extracción y preservación del reborde, para recibir en el mismo sitio un implante dental en sustitución protésica. En la primera etapa quirúrgica, se realizaron las extracciones dentales y la preservación del reborde alveolar, utilizando como sustituto óseo los dientes extraídos y procesados con un sistema automático. En la segunda etapa quirúrgica, se realizó una biopsia ósea incisional en cada sitio injertado, los lechos óseos fueron recapitulados en un protocolo de fresado que permitió la colocación del implante dental y los especímenes óseos recolectados fueron preparados para su análisis. Los resultados histológicos de las biopsias óseas en todos los casos mostraron partículas remanentes del injerto dental, conformadas por dentina, parcialmente reabsorbidas, con margenes superficiales irregulares y en estrecho contacto con depósitos de hueso de reciente formación en transición hacia hueso laminar maduro, en el cual se observaron osteocitos bien diferenciados. Los resultados inmunohistoquímicos mostraron una expresión positiva moderada de osteopontina en los bordes de las partículas del injerto dental integrado, al interior del espacio peritubular dentinario y en las interfases de contacto osteodental. En conclusión, la evidencia del estudio muestra que el injerto dental autólogo es un sustituto óseo biocompatible, que provee un andamio osteoconductivo promotor de la adhesión y migración de las células óseas para la osteogénesis local y que está asociado a la expresión modera in situ de osteopontina, la cual mostro una alta afinidad con el tejido dental mineralizado, sugiriendo propiedades osteoinductivas in situ.

15.
Journal of Prevention and Treatment for Stomatological Diseases ; (12): 115-118, 2021.
Article in Chinese | WPRIM | ID: wpr-842948

ABSTRACT

@#The rapid absorption of labial alveolar bone after tooth extraction not only reduces the aesthetic effect of implant repair but also affects the long-term success rate of implants. The socket shield technique is reported as the latest alveolar preservation technique in the aesthetic zone from both domestic and international case reports and shows a high success rate of short-term osseointegration and excellent aesthetic effects. However, some investigations have shown short- and long-term complications with the socket shield technique, such as failure of osseointegration, loss of crestal bone and buccal bone, inflammation, etc. In this review, the socket shield technique will be reported in detail with its pros and cons. Although the socket shield technique has achieved good clinical effects and short-term success rates in many cases, there are still no conclusions regarding the surgical procedure, such as the thickness, the position of the shield, whether to put the graft material between the shield and implant, etc. Due to the lack of long-term research or a large amount of clinical literature support and technical sensitivity, the socket shield technique should be carefully used in clinical application to reduce unexpected risks.

16.
Journal of Prevention and Treatment for Stomatological Diseases ; (12): 95-105, 2021.
Article in Chinese | WPRIM | ID: wpr-837749

ABSTRACT

Objective @#To evaluate the effect of platelet-rich fibrin (PRF) on alveolar ridge preservation after tooth extraction.@*Methods@#Randomized controlled trials (RCTs) published before August 25, 2020 about the use of PRF after tooth extraction were searched through the PubMed, Embase, Cochrane Library, HowNet, Wanfang, CBM databases and clinical trial registration centers in China and the United States. Outcome indicators included in the studies included dry socket occurrence, alveolar bone resorption in the horizontal and vertical directions, and the percentage of new bone. Meta-analysis was conducted with Review Manager Version 5.3 software.@*Results@# A total of 706 studies were retrieved. After screening, 8 studies were analyzed quantitatively. Meta-analysis results showed that PRF could reduce the absorption of alveolar bone after tooth extraction, which reduced the horizontal bone mass (WMD=-0.71, 95% CI=-1.11 to -0.32, P < 0.05) and buccal (WMD=-1.38, 95% CI =-1.87 to -0.88, P < 0.05) and lingual sides (WMD=-0.49, 95% CI=-0.92 to -0.06, P < 0.05) and increased the percentage of new bone (SMD=1.24, 95% CI =0.25 to 2.23, P < 0.05). However, there was no significant difference in preventing the occurrence of dry socket (RD < 0.01, 95% CI=-0.05 to 0.04, P=0.95) and reducing bone absorption in the vertical direction of mesial (WMD=-0.11, 95% CI=-1.17 to 0.95, P=0.84) and distal (WMD=-0.66, 95% CI=-1.93 to 0.60, P=0.30) alveolar ridge after tooth extraction. @*Conclusion @# Using PRF alone after tooth extraction can effectively preserve bone mass in the horizontal direction of the alveolar ridge and the vertical direction of the buccal and lingual sides.

17.
RGO (Porto Alegre) ; 69: e20210059, 2021. tab, graf
Article in English | LILACS-Express | LILACS, BBO | ID: biblio-1351399

ABSTRACT

ABSTRACT Objective: The aim of this cross-sectional study was to evaluate the anatomical characteristics of edentulous residual ridges in stone casts of complete dentures users and assess correlations with masticatory efficiency. Methods: The sample included 74 study casts, of which 37 were higher and 37 bottom. Measurements were performed using a drypoint compass and a transparent ruler. Arches and ridges of maxillae and mandibles were classified into small, medium, and large. Masticatory efficiency was obtained by the sieve method with the old prostheses and 3 months after placement of new prostheses. The correlations between the anatomical variables of the ridges and arches (height, width and size) and masticatory efficiency were verified by the Spearman correlation test. Significant differences in masticatory efficiencies were assessed by the Wilcoxon test. Results: People with larger maxillary alveolar ridge presented better masticatory performance with old and new dentures. There was no correlation between maxillary ridge width and size with masticatory efficiency, but a correlation was found between maxillary arch width and masticatory efficiency evaluated with the old dentures. Conclusions: With the new dentures, the correlation had a tendency for significance. For the mandible, no correlation was found between height, width, and size of the ridge or with width, length, and size of the arch and masticatory efficiency. In addition, there was no significant difference between masticatory efficiencies evaluated with the old and new prostheses. For the maxilla, ridge height and arch width influence masticatory efficiency. For the mandible, the anatomy had little influence on masticatory performance.


RESUMO Objetivo: Este estudo transversal objetivou avaliar as características anatômicas de rebordos residuais de usuários de próteses totais em gesso pedra e avaliar correlações com a eficiência mastigatória. Métodos: A amostra incluiu 74 modelos de estudo, sendo 37 superiores e 37 inferiores. As medidas foram realizadas com um compasso de ponta seca e régua transparente. Os arcos e rebordos da maxila e mandíbula foram classificados em pequenos, médios e grandes. A eficiência mastigatória foi obtida pelo método da peneira com as próteses antigas e 3 meses após a instalação das próteses novas. As correlações entre as variáveis anatômicas dos rebordos e arcos (altura, largura e tamanho) e a eficiência mastigatória foram verificadas pelo teste Spearman. Diferenças significativas nas eficiências mastigatórias foram avaliadas pelo teste de Wilcoxon. Resultados: Pessoas com crista alveolar maxilar alta apresentaram melhor desempenho mastigatório com próteses novas e antigas. Não houve correlação entre a largura e o tamanho da crista maxilar com a eficiência mastigatória, mas foi encontrada uma correlação entre a largura do arco maxilar e a eficiência mastigatória avaliadas com as próteses antigas. Para a mandíbula, não foi encontrada correlação entre altura, largura e tamanho da crista ou com largura, comprimento e tamanho do arco e eficiência mastigatória. Além disso, não houve diferença significativa entre as eficiências mastigatórias avaliadas com as próteses antigas e novas. Conclusão: Para a maxila, a altura da crista e a largura do arco influenciam a eficiência mastigatória. Para a mandíbula, a anatomia teve pouca influência no desempenho mastigatório.

18.
Dental press j. orthod. (Impr.) ; 25(5): 24-29, Sept.-Oct. 2020. tab, graf
Article in English | LILACS, BBO | ID: biblio-1133693

ABSTRACT

ABSTRACT Objective: The present study aimed at comparing the external lateral root resorption (ELRR) and external apical root resorption (EARR) between teeth moved through the atrophic edentulous ridge and those undergoing the usual orthodontic movement. Methods: Fifty-four premolars were evaluated, where 27 of them had been moved toward the edentulous ridge (Group 1) and 27 from the same patient, had not been translated, which comprised the control group (Group 2). ELRR was evaluated by 0-3 scores and EARR was evaluated by 0-4 scores, before and after movement. Measurements were compared by Kruskal-Wallis and Student-Newman-Keuls tests. Results: ELRR increased statistically only in the Group 1 (p< 0.05). After orthodontic treatment, it was observed that almost 56% (n = 15) of teeth in Group 1 presented scores 2 and 3, while Group 2 presented scores 2 and 3 in about 11% (n= 3) of the teeth. EARR increased in both groups after orthodontic movement, however, statistically analyses showed no significant differences between groups (p> 0.05). Conclusions: Orthodontic movement into the atrophic edentulous ridge is subject to a greater lateral external root resorption.


RESUMO Objetivo: O presente estudo teve como objetivo comparar a reabsorção radicular lateral externa (RRLE) e a reabsorção radicular apical externa (RRAE) em dentes movimentados sobre o rebordo edêntulo atrófico e naqueles submetidos à movimentação ortodôntica usual. Métodos: Foram avaliados 54 pré-molares, sendo 27 deles movimentados em direção ao rebordo edêntulo (Grupo 1) e 27 (dos mesmos pacientes) não transladados, que compuseram o grupo controle (Grupo 2). A RRLE foi avaliada por meio de escores de 0 a 3, e a RRAE foi avaliada por meio de escores de 0 a 4, antes e depois do tratamento. As medidas foram comparadas por meio dos testes de Kruskal-Wallis e de Student-Newman-Keuls. Resultados: O escore da RRLE aumentou estatisticamente apenas no Grupo 1 (p< 0,05). Após o tratamento ortodôntico, observou-se que quase 56% (n = 15) dos dentes do Grupo 1 apresentaram escores 2 e 3, enquanto o Grupo 2 apresentou escores 2 e 3 em cerca de 11% (n = 3) dos dentes. O escore da RRAE aumentou em ambos os grupos após a movimentação ortodôntica; entretanto, as análises estatísticas não mostraram diferenças significativas entre os grupos (p> 0,05). Conclusões: Dentes submetidos à movimentação ortodôntica sobre rebordo edêntulo atrófico estão sujeitos a uma maior reabsorção radicular externa lateral.


Subject(s)
Humans , Root Resorption , Bicuspid , Root Resorption/etiology , Root Resorption/diagnostic imaging , Tooth Movement Techniques
19.
Braz. dent. j ; 31(5): 458-465, Sept.-Oct. 2020. tab, graf
Article in English | LILACS, BBO | ID: biblio-1132332

ABSTRACT

Abstract This study aims to evaluate the post-extraction alveolar bone reconstruction amongst 12 patients exhibiting loss of buccal bone plate in a tooth of the anterior region of the maxilla using the prosthetically-driven alveolar reconstruction technique (PDAR). In PDAR, a partial fixed provisional prosthesis (PFPP [conventional or adhesive]) with a specially designed pontic maintains the clot in a mechanically stable position during alveolar regeneration. Moreover, the pontic design, in hourglass shape and located in the subgingival area, also prevents gingival margins from collapsing. Gingival recession was evaluated through the 6-month healing period. Cone beam computed tomography (CBCT) was performed 1 month before and 8 months after PDAR treatment. For the primary outcome, in the panoramic imaging, the central area of bone defect in each tooth was selected for linear measurements. Measurements of the vertical buccal bone gain and the gain in thickness in the alveolar bone crest were obtained 8 months after PDAR. Descriptive statistics and intraclass correlation coefficient analysis were conducted. After treatment, all patients showed bone formation (a mean vertical gain of 7.1±3.7 mm, associated with a horizontal mean gain of 4.5±1.4 mm in the alveolar bone crest). The intraclass correlation coefficient for the measurements performed using CBCT was 0.999. No gingival recession, greater than 1 mm, was observed. Lower-morbidity procedures without the use of biomaterials may be a useful in post-extraction alveolar ridge regeneration and/or preservation. PDAR promoted alveolar bone formation without flaps, grafts and membranes.


Resumo Este estudo teve como objetivo avaliar a reconstrução do osso alveolar após extração em 12 pacientes com perda da tábua óssea vestibular em dentes na região anterior da maxila usando a técnica da reconstrução alveolar proteticamente guiada (RAPG). Na RAPG, uma prótese parcial fixa provisória (PPFP [convencional ou adesiva]) com um pôntico com design específico mantém o coágulo numa posição mecanicamente estável. Além disso, o design do pôntico, com formato de ampulheta e localizado na área subgengival, também previne o colapso das margens gengivais. A recessão gengival foi avaliada durante o período de cicatrização de 6 meses. Tomografias computadorizadas cone beam (TCCB) foram feitas 1 mês antes e 8 meses após o tratamento com a RAPG. Para o desfecho primário, nas imagens panorâmicas, a área central do defeito ósseo em cada dente foi selecionada para as medições lineares. As medições do ganho vertical ósseo vestibular e do ganho em espessura na crista óssea alveolar foram realizadas. A análise estística descritiva e a análise do coeficiente de correlação intraclasse forma realizados. Após o tratamento, todos os pacientes apresentaram formação óssea (ganho vertical médio de 7,1±3,7 mm, associado a ganho horizontal médio de 4,5±1,4 mm na crista óssea alveolar). O coeficiente de correlação intraclasse foi de 0,999. Nenhuma retração gengival acima de 1 mm foi observada. Procedimentos com baixa morbidade sem o uso de biomateriais podem ser úteis na regeneração/preservação do rebordo após as extrações. A RAPG promove a formação do osso alveolar sem o uso de retalhos, enxertos e membranas.


Subject(s)
Humans , Alveolar Bone Loss/diagnostic imaging , Tooth Socket , Tooth Extraction , Retrospective Studies , Cone-Beam Computed Tomography , Alveolar Process/surgery , Alveolar Process/diagnostic imaging , Maxilla
20.
J. oral res. (Impresa) ; 9(4): 336-349, ago. 31, 2020. ilus, tab
Article in English | LILACS | ID: biblio-1179158

ABSTRACT

Background: Osseointegration allowed for a breakthrough in biomaterials and techniques and it has contributed to increased application of dental implants. However, insufficient bone level is a frequent problem and it creates an anatomically less favourable base for implant placement. The first surgical procedure should comprise the reconstruction of the alveolar bone height. CoCrMo alloys are nowadays considered as highly corrosion resistant and biocompatible materials in dentistry, and therefore has been suggested as a suitable biomaterial for guided bone regeneration and tissue engineering. Aim: To determine the use of CoCrMo alloy for implantable devices in oral and maxillofacial surgery and to discuss the potential of this alloy for bone regeneration and repair through a scoping review. Material and methods: The search was done by using various databases including PubMed, Thomson Reuters and Scopus. We selected English literature related to studies reporting the CoCrMo properties and manufacturing processes and findings related to bone-forming techniques. Data was compared qualitatively. Results: 90 studies were selected according to the inclusion criteria. We reported different manufacturing techniques and their advantages related to mechanical, chemical and biocompatible properties. Conclusion: Improved tissue reactions of CoCrMo implant devices can be acquired by the application of novel techniques and surface modifications. Moreover, several processes have demonstrated to improve the in vitro and in vivo biocompatibility of the CoCrMo alloy to promote the attachment, proliferation and guided differentiation of seeding cells.


Antecedentes: La osteointegración ha permitido un gran avance en biomateriales y técnicas, y ha contribuido un mayor uso de implantes dentales. Sin embargo, la existencia de un nivel óseo insuficiente es un problema frecuente y crea una base anatómicamente menos favorable para la colocación de implantes. El primer procedimiento quirúrgico debe comprender la reconstrucción de la altura del hueso alveolar. Las aleaciones de CoCrMo se consideran hoy en día como materiales altamente resistentes a la corrosión y biocompatibles en odontología y, por lo tanto, se ha sugerido como un biomaterial adecuado para la regeneración ósea guiada y la ingeniería de tejidos. Objetivo: Determinar el uso de la aleación CoCrMo para dispositivos implantables en cirugía oral y maxilofacial y discutir sobre el potencial de esta aleación para la regeneración y reparación ósea a través de una revisión de alcance. Material y Métodos: La búsqueda se realizó utilizando varias bases de datos, incluidas PubMed, Thomson Reuters y Scopus. Se seleccionó literatura inglesa relacionada con estudios que informan sobre las propiedades de CoCrMo y los procesos de fabricación y los hallazgos relacionados con las técnicas de formación de huesos. Los datos se compararon cualitativamente. Resultados: Se seleccionaron 90 estudios según los criterios de inclusión. y se reportaron diferentes técnicas de fabricación y sus ventajas relacionadas con propiedades mecánicas, químicas y biocompatibles. Conclusión: Las reacciones tisulares mejoradas de los dispositivos de implante CoCrMo pueden adquirirse mediante la aplicación de nuevas técnicas y modificaciones de la superficie. Además, varios procesos han demostrado mejorar la biocompatibilidad in vitro e in vivo de la aleación CoCrMo para promover la unión, proliferación y diferenciación guiada de las células de siembra.


Subject(s)
Humans , Surgery, Oral/methods , Biocompatible Materials , Alloys , Bone Regeneration , Dental Implants , Alveolar Ridge Augmentation
SELECTION OF CITATIONS
SEARCH DETAIL